Improved bolus arrival time and arterial input function estimation for tracer kinetic analysis in DCE-MRI
نویسندگان
چکیده
منابع مشابه
Estimation of contrast agent bolus arrival delays for improved reproducibility of liver DCE MRI
Delays between contrast agent (CA) arrival at the site of vascular input function (VIF) sampling and the tissue of interest affect dynamic contrast enhanced (DCE) MRI pharmacokinetic modelling. We investigate effects of altering VIF CA bolus arrival delays on liver DCE MRI perfusion parameters, propose an alternative approach to estimating delays and evaluate reproducibility. Thirteen healthy v...
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C. Yang, W. M. Stadler, M. Medved, G. S. Karczmar University of Chicago, Chicago, IL, United States Introduction: Accurate estimation of the arterial input function (AIF) is essential for quantitative analysis of DCE-MRI data. We have previously demonstrated that a common AIF can be estimated from the contrast agent concentration versus time curves (Ct(t)) in two reference tissues with differen...
متن کاملImproved hepatic arterial fraction estimation using cardiac output correction of arterial input functions for liver DCE MRI.
Liver dynamic contrast enhanced (DCE) MRI pharmacokinetic modelling could be useful in the assessment of diffuse liver disease and focal liver lesions, but is compromised by errors in arterial input function (AIF) sampling. In this study, we apply cardiac output correction to arterial input functions (AIFs) for liver DCE MRI and investigate the effect on dual-input single compartment hepatic pe...
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ژورنال
عنوان ژورنال: Journal of Magnetic Resonance Imaging
سال: 2009
ISSN: 1053-1807,1522-2586
DOI: 10.1002/jmri.21624